DEC 16, 2025
The Supplement Tier List
The supplement industry is a multi-billion dollar machine built largely on marketing, not science. We are here to save you money.
This tier list is based on Strength of Evidence.
S-Tier: The "Big Three" (Proven & Effective)
- Evidence: Overwhelming meta-analyses support these.
- Cost-Benefit: Excellent.
| Supplement | What it Does | Dose |
|---|---|---|
| Creatine Monohydrate | Increases power output, muscle hydration, and cognitive function. | 5g daily. Anytime. |
| Caffeine | Potent stimulant. Reduces perceived effort and increases force production. | 3-6mg/kg (approx 200-400mg) pre-workout. |
| Whey Protein | Convenient, high-quality protein to hit daily macros. | 20-40g post-workout or as needed. |
A-Tier: Useful for Specific Goals
- Evidence: Strong, but benefits are situational.
- Cost-Benefit: Good.
- Citrulline Malate: Increases blood flow (pump) and endurance. Great for high-volume bodybuilders. (Dose: 6-8g).
- Beta-Alanine: "The tingle stuff." Buffers acid in muscles. Only helps for sets lasting >60 seconds (15+ reps). (Dose: 3-5g daily).
- Electrolytes (Sodium/Potassium): Critical if you sweat heavily or train for long durations. (Dose: to taste).
B-Tier: The "Maybe" Pile
- Evidence: Mixed or minor.
- Cost-Benefit: Low.
- Multivitamins: An "insurance policy" for bad diets, but whole food is better.
- Fish Oil: Good for general health/joints, but won't directly build muscle.
- Ashwagandha: Can lower cortisol and mildly boost testosterone in stressed individuals.
F-Tier: The Garbage Bin (Do Not Buy)
- Evidence: Disproven or unsafe.
- BCAAs (Branched Chain Amino Acids): Completely useless if you eat enough protein. You need all 9 essential amino acids to build muscle, not just 3.
- Testosterone Boosters: Usually herbal blends (Tribulus, Fenugreek) that boost libido but have zero impact on actual free testosterone levels or muscle growth.
- Fat Burners: Mostly just expensive caffeine with pepper extract. The only things that truly burn fat are illegal or a calorie deficit.
The Bion Philosophy
Supplements are the top 1% of the pyramid.
- 90%: Training & Caloric Surplus.
- 9%: Sleep & Recovery.
- 1%: Supplements.
Bion focuses on the 99%—tracking your progressive overload and managing your fatigue. Master that first.
FREQUENTLY_ASKED_QUESTIONS
Currently: D-Tier. The animal data looks promising, but human trials have failed to show any significant muscle building effect over placebo. Save your money until more evidence exists.